Partitioning and Kinetics of Methylmercury among Organs in Captive Mink ( Neovison vison ): A Stable Isotope Tracer Study

•Double spiking with stable isotopes of methylHg was used to simultaneously measure uptake and elimination in different organs.•The isotope data demonstrate clearly both the uptake and loss of methylHg across the blood–brain barrier.•There was a lag time between peak blood concentration and peak brain of methylHg.•Irrespective of blood concentration the partition coefficient between blood and brain was approximately 2.5.•Half-lives for methylHg in brain, liver and kidney ranged between 10 and 15 days.