Angiosarcoma of The Maxilla: Case Report

Angiosarcomas are aggressive malignant neoplasms that can mimic other malignant neoplasms. Man, 58, underwent radiographic examination that revealed a radiolucent area with irregular borders occupying the region of the right maxillary first premolar and extending to the molar region. The clinical diagnosis suggested was osteosarcoma. An incisional biopsy was performed. The histological examination showed a malignant neoplasm composed of irregular vascular spaces lined with atypical epithelioid cells and moderate mitotic activity. On immunohistochemical examination, tumor cells were positive for factor CD31, CD34, and smooth muscle actin, but were nonreactive with AE1/AE3 and S-100 protein. The histopathological diagnosis established was low-grade angiosarcoma. The patient was referred for treatment of head and neck cancer. (Supported: CNPq N° 141641/2013-4).