Bone Mineral Density (BMD) Improves in Survivors in Their Second Decade Post-Allogeneic Stem Cell Transplantation and Is Influenced By Body Mass Index (BMI) and Age

Sawa Ito,Neil Dunavin,Eleftheria Koklanaris,Priyanka A Pophali,Xin Tian,Colin Wu,Natasha A Jain,Prathima Anandi,Minoo Battiwalla,A John Barrett,Bipin N Savani,Robert Q Le

Biology of Blood and Marrow Transplantation（2015）

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Abstract

Rapid and profound BMD loss occur in the first year after allogeneic stem cell transplantation (SCT) and attributed to steroid exposure, chronic GVHD (cGVHD), conditioning, age and gender. However, changes in BMD in very long-term survivors are not well understood. We evaluated survivors by serial DEXA scans to determine the kinetics as well as to identify the factors influencing long-term BMD beyond 3 years post SCT.

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Key words

body mass,body mass index,transplantation,bmi,post-allogeneic

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