Candidate Genes Polymorphism and Its Association to Prolificacy in Chinese Goats

To find the candidate gene concerned with prolificacy in goats, the most part nucleotide sequence of four genes,including GDF9 gene, BMP15 gene, BMPR1B gene, and INH? gene were identified in three goat breeds for theirprobable association to the high fecundity. The results showed that none of polymorphism of GDF9 gene, BMP15 geneand BMPR1B gene was tested in goats, and one mutation was detected in INH? gene. The genotype distributions ofINH? gene were significantly difference between year-round estrous goat breeds and seasonal estrous goat breedsrevealing the association to the prolificacy in goats.