Hepatitis B viral load in dried blood spots: A validation study in Zambia

Michael J. Vinikoor,Samuel Zürcher,Kalo Musukuma,Obert Kachuwaire, Andri Rauch,Benjamin H. Chi, Meri Gorgievski,Marcel Zwahlen,Gilles Wandeler

Journal of Clinical Virology（2015）

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摘要

•Dried blood spots (DBS) were tested in a Zambian lab for hepatitis B viral load.•There was strong agreement between HBV viral loads in DBS and plasma samples.•DBS viral loads were on average 1.5logIU/ml lower than plasma viral loads.•HBV was detected in DBS 98.2% of the time at a plasma viral load ≥2,000IU/ml.

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关键词

Hepatitis B virus,Dried blood spots,Africa,HIV/AIDS,Viral load

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