Development of a sensitive enzyme-linked immunosorbent assay for the measurement of biologically active etanercept in patients with ankylosing spondylitis
Journal of Chromatography B（2016）
Abstract
•A sensitive ELISA for the measurement of biologically active etanercept was built.•Accurate PK data of biologically active etanercept were achieved with this method.•This new assay was successfully applied to the PK study of etanercept in patients.
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Key words
Ankylosing spondylitis,Biologically active,Enzyme-linked immunosorbent assay,Etanercept,Pharmacokinetics
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