PRS41 – Health Economic Benefit Of Including Component Resolved Diagnostics (Crd) (Immunocap Isac) In In Vitro Diagnostic (Ivd) Algorithm In Prospective Trial With Suspected Food Allergic School Children In Finland
Value in Health(2014)
Abstract
Aim of study, in accordance to Finnish Allergy Program 2008-2018, is to decrease food avoidance diets by 50 %. Here focus is in algorithm with IVD and patient history in primary care school children. Health economic benefit of CRD, ISAC, is evaluated. Database analysis at Härkätie Primary Care Unit, including 2317 school children in Finland indicated that 199 children (8.6%) are on avoidance diet ex. celiac disease. There is 37 (1.6 %) milk and 32 (1,4%) egg free diets. Peanut and hazelnut allergy is indexed for 39 children and 6 are indicated as soya allergic. History of anaphylaxis was noted in 7. Avoidance recommendation is provided by parents and has direct impact in costs and patient’s quality of life. The 199 children were contacted by letter, and 36 (18 %) were interviewed by physician. Of those, 24 children agreed to take part in the study with IVD (67%). An unnecessary diet was concluded for 15, which is 63% of children included in the study: cow’s milk 7 (29%), peanut 5 (21%), egg 3 (13%), fish 1 (4%) and fruits 1 (4%). Peanut could be reintroduced to all children after CRD, egg and milk after specific IgE IVD. Prior to the introduction of food a secondary care specialist food provocation was performed to confirm the IVD result. CRD ISAC was beneficial in 54% of the cases and in 21% of the cases it was critical for decision making. The aim of the study was reached as avoidance diets decreased by 63%. The results indicate, even with low patient recruitment, it is likely that introducing ISAC IVD to traditional diagnostic algorithm can be considered cost-effective, with an average cost per avoided unnecessary diet for 480 EURs per child. To confirm the findings a larger study will be executed.
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Key words
immunocap isac,vitro diagnostics,component resolved diagnostics
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