The interleukin-1β-511 T > C (rs16944) gene polymorphism is associated with risk of developing silent myocardial ischemia in diabetic patients

Gilberto Vargas-Alarcón,Miguel Cruz-López,Adán Valladares,Edith Álvarez-León,Teresa Juárez-Cedillo,Óscar Pérez-Méndez,Jorge Escobedo de-la-Peña,Galileo Escobedo,Jose Manuel Fragoso

Immunology Letters（2015）

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摘要

•The rs16944 polymorphism is associated with risk of developing SMI in diabetic patients.•Under four inheritance models the CC and CT genotypes of the rs16944 SNP increased risk of developing SMI.•The haplotypes CTCC, CCTC, CCCT and CTCC increased risk of developing SMI in diabetic patients.

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关键词

SMI,IL-1β,IL-1F10,IL-1ra,SNP,MAF

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