Impact of introducing guidelines for thrombolysis of submassive pulmonary embolism at a large UK teaching hospital

Pulmonary embolism (PE) is a significant cause of death with 10% of patients dying within 3 months [1]. Multiple studies now advocate the use of thrombolysis (TPA) in both massive and submassive PE [1,2]. This audit assessed the impact of introducing a guideline allowing for thrombolysis of submassive and massive PE at a large UK teaching hospital.