Characterization of top-down ETD in a travelling-wave ion guide
Methods(2015)
摘要
•ETD on a Synapt instrument allows efficient top-down fragmentation of peptides and proteins.•Charge reduction reactions lead to low fragment charge states, simplifying assignment.•Extent of ion–ion reactions is mainly controlled by T-wave amplitude and velocity.•Ion mobility coupling allows fragment assignment to a specific precursor.
更多查看译文
关键词
Top-down mass spectrometry,Intact protein mass spectrometry,Top-down sequencing,Electron transfer dissociation,Ion mobility
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要