Quality of life measured by the Comprehensive Headache-related Quality of life Questionnaire improves after successful detoxification of medication overuse headache

Background: Medication overuse headache (MOH) affects 1% of the population and is notoriously difficult to treat. The cornerstone of its treatment is detoxification supplemented by adequate preventive measures. Measuring quality of life (QOL) is an important means of assessing the impact of headache, and may be used as an endpoint in therapeutic trials. The Comprehensive Headache-related Quality of life Questionnaire (CHQQ) is a new headache-specific QOL instrument that has been validated in migraine and tension type headache.