Elevated miR-155 expression induces immunosuppression via CD39+ regulatory T-cells in sepsis patient

Jingquan Liu,Kai Shi,Minhua Chen,Liang Xu,Jun Hong,Bangchuan Hu,Xianghong Yang,Renhua Sun

International Journal of Infectious Diseases（2015）

引用 48|浏览12

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摘要

•MicroRNA-155 was significantly up-regulated in sepsis patients.•A high level of microRNA-155 was an indicator of a severe condition and poor prognosis in sepsis patients.•The percentage of CD39+ Tregs was elevated in sepsis patients.•MicroRNA-155 induced the increase in percentage of CD39+ Tregs.

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关键词

Sepsis,MicroRNA,Regulatory T-cell,MicroRNA microarray,Outcome

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