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Lack of association of rs3798220 with small apolipoprotein(a) isoforms and high lipoprotein(a) levels in East and Southeast Asians

Mahmoud Khalifa,Asma Noureen, Kathrin Ertelthalner,Ahmad Reza Bandegi,Rhena Delport, Wance J.J. Firdaus,Finney S. Geethanjali,Kalpana Luthra, Orawan Makemaharn,Richard W.C. Pang,Abdel-Halim Salem,Jun Sasaki,Wulf Schiefenhoevel,Arno Lingenhel,Florian Kronenberg,Gerd Utermann,Konrad Schmidt

Atherosclerosis（2015）

Cited 19|Views29
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Abstract
•rs3798220 is associated with long rather than short KIV-2 CNV alleles in Asians.•rs3798220 variant alleles are not associated with high Lp(a) in these populations.•This likely explains why this SNP in LPA is not associated with CAD in Asians.
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Key words
Copy number variation,Coronary artery disease,Genetic variation,Lipoprotein(a),Population genetics
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