IMPACT OF LOSS OF FUNCTION VARIANT OF BETATROPHIN ON ADVANCED CORONARY ARTERY DISEASE AMONG DIABETIC PATIENTS IN JAPAN

A. Nohara,K. Yagi,J. Liu,S. Okazaki,M. Yoshida, M. Mori,C. Nakanishi,M. A. Kawashiri,A. Inazu, M. A. Yamagishi,H. Mabuchi

Atherosclerosis（2014）

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Abstract

Objectives: Betatrophin is recently identified hormone that controls pancreatic ß cell proliferation and lipid metabolism, but its roles in human disease are not established. We hypothesized that genetic variant of this gene may play role in coronary artery disease (CAD).

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Key words

coronary artery disease,betatrophin,advanced coronary artery disease,diabetic patients

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