ChemInform Abstract: N‐Chlorophthalimide as a Mild and Efficient Chlorination Reagent in the Gassman ortho Alkylation of Aromatic Amines. Synthesis of 3‐(Methylthio)oxindoles.

Marcin Cybulski,Adam Formela,Izabela Fokt

Cheminform（2015）

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摘要

The modified mild conditions for Gassman ortho alkylation of aromatic amines allow the isolation of the intermediate α‐amidosulfides (III), which are cyclized to produce 3‐(methylthio)oxindoles.

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关键词

aromatic amines,efficient chlorination reagent,synthesis,alkylation,n-chlorophthalimide

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