ChemInform Abstract: ZrCl4‐Catalyzed C—O Bond to C—N Bond Formation: Synthesis of 1,2,3‐Triazoles and Their Biological Evaluation.

Gangavaram V M Sharma, Kandikonda Suresh Kumar,Buddana Sudheer Kumar,Sheri Venkata Reddy,Reddy Shetty Prakasham,Helmut Hugel

Cheminform（2015）

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摘要

Abstract A simple and efficient protocol was developed for the synthesis of aryl azides directly from aryl carbinols using ZrCl4 as a Lewis acid catalyst. The azides were converted to novel triazoles under click reaction conditions, which were evaluated for their antimicrobial activity against various strains.

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关键词

Antimicrobial activity,click chemistry,1,2,3-triazole,zirconium(IV) chloride

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