ChemInform Abstract: A General Stereocontrolled Synthesis of cis-2,3 Disubstituted Pyrrolidines and Piperidines.

Cheminform（2010）

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Abstract A general synthetic method is reported for the preparation of cis-2,3-disubstituted pyrrolidines and piperidines from readily available acyclic precursors. The key reaction involves the stereoselective reduction of a cyclic imine controlled by the C-3 substituent.

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Diversity-Oriented Synthesis

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