ChemInform Abstract: New Synthetic Route of Two Active Isomeric Metabolites of Erlotinib and Their Bioactivity Studies Against Several Tumor Cell Lines.

Hanqing Li,Mengyao Li,Zaiquan Li,Liang Li,Shanshan Bi,Chenhui Deng,Rui Chen,Tianyan Zhou,Wei Lu

Cheminform（2011）

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摘要

The title metabolites M-13 (Ia) and M-14 (Ib) possess antiproliferative activities against BGC-823, Bel-823, KB tumor cell lines and EGFR tyrosine kinase over-expression tumor cell lines.

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