Efficient One-Pot Synthesis of 4-Aroyl-2-pyrones: Nucleophilic Addition of Active Methylene Groups to 1,2-Diaroylacetylenes
Chem Inform(2012)
摘要
An efficient synthesis of 3,6-disubstituted-4-aroyl-2-pyrones in a single-step reaction through Michael addition of 1,2-diaroylacetylenes with active methylene compounds in the presence of NaH in dimethylsulfoxide at room temperature is reported. The structures have been confirmed by spectral data analyses.
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关键词
4-Aroyl-2-pyrones,1,2-diaroylacetylenes,Michael addition
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