Efficient One-Pot Synthesis of 4-Aroyl-2-pyrones: Nucleophilic Addition of Active Methylene Groups to 1,2-Diaroylacetylenes

An efficient synthesis of 3,6-disubstituted-4-aroyl-2-pyrones in a single-step reaction through Michael addition of 1,2-diaroylacetylenes with active methylene compounds in the presence of NaH in dimethylsulfoxide at room temperature is reported. The structures have been confirmed by spectral data analyses.