ChemInform Abstract: Regioselective Synthesis of 1,3,5‐ and 1,3,4,5‐Substituted Pyrazoles via Acylation of N‐Boc‐N‐Substituted Hydrazones.

Alessandro Tinarelli,Paolo Righi,Goffredo Rosini,Daniele Andreotti,Roberto Profeta,Simone Spada

Cheminform（2011）

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摘要

Acylation of title hydrazones, e.g. (I), proceeds with either acyl chlorides or esters (II) to give hydrazones which undergo TFA-promoted cyclization to pyrazoles like (IV).

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