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Efficient Cesium Carbonate Promoted N-Alkylations of Aromatic Cyclic Imides Under Microwave Irradiation

Mercedes Isasmendi Escudero,Lautaro Kremenchuzky,Isabel A Perillo,Hugo Cerecetto,Maria M Blanco

Cheminform（2011）

Cited 10|Views2
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Abstract
We present here an efficient and simple method for the N-alkylation of aromatic cyclic imides employing cesium carbonate as the base in anhydrous N,N-dimethylformamide at low temperatures (20-70 degrees C). The employment of microwave irradiation presents noteworthy advantages over conventional heating. The method is compatible with base labile functional groups.
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Key words
cesium carbonate,imides,N-alkylation,microwave irradiation,nitrogen heterocycles
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