ChemInform Abstract: Potent Mammalian Topoisomerase II Inhibitors: 1‐Cyclopropyl‐6,8‐ difluoro‐1,4‐dihydro‐7‐(2,6‐dimethyl‐4‐pyridinyl)‐4‐substituted‐ quinolines.
Cheminform(1995)
Abstract
Abstract A series of novel 4-substituted-1,4-dihydro-quinolines 3 were prepared and found to exhibit moderate to excellent mammalian topo II inhibitory activity. Among the compounds prepared, in general, the nitrogen analogues are the most active compounds and the sulfur analogue is the least active one.
MoreTranslated text
Key words
inhibitors,cheminform abstract
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined