Synthesis of 3‐Substituted Tetrahydrofuran and 4‐Substituted Tetrahydropyran Derivatives by Cyclization of Dicarboxylic Acids with InBr3/TMDS
Cheminform（2012）
Abstract
An efficient reduction followed by cyclization of diacid compounds with the InBr3/TMDS system is reported. This system allows the formation of five- and six-membered ring ethers substituted in the 3- or 4-position.
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Key words
Cyclization,Indium,Oxygen heterocycles,Carboxylic acids,Reduction
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