ChemInform Abstract: Silica-Sulfuric Acid Catalyzed Nitrodeiodination of Iodopyrazoles.
Cheminform(2013)
Abstract
We report here the synthesis of nitropyrazoles in good to excellent yields from iodopyrazoles over silica–sulfuric acid catalyst for the first time. The present procedure require less acid, offers a simplified workup procedure, and may be applied for the nitration of a wide variety of iodoazoles in drug and pharmaceutical industries.
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Key words
substitution reactions
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