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ChemInform Abstract: Silica-Sulfuric Acid Catalyzed Nitrodeiodination of Iodopyrazoles.

P. Ravi,Girish M. Gore,Arun K. Sikder,Surya P. Tewari

Cheminform（2013）

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Abstract
We report here the synthesis of nitropyrazoles in good to excellent yields from iodopyrazoles over silica–sulfuric acid catalyst for the first time. The present procedure require less acid, offers a simplified workup procedure, and may be applied for the nitration of a wide variety of iodoazoles in drug and pharmaceutical industries.
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substitution reactions
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