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Reconstitute the damaged heart via the dual reparative roles of pericardial adipose-derived flk-1+ stem cells

Xiaoming Wang,Xueqing Liu,Hui Zhang,Liangming Nie,Min Chen,Zhaoping Ding

International Journal of Cardiology（2016）

Cited 7|Views8
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Abstract
•Flk-1 positive cells gave rise to both myogenic and angiogenic precursors.•In vivo transplantation yielded structural and functional repair for injured heart.•Neoangiogenesis befell preferentially on microvasculature•Neomyogenesis via the proliferation of pre-existing cardiomyocytes.•Flk-1 positive cells are attacking donor cells to reconstitute the damaged heart.
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pADSC,flk-1,cTnT,vWF,CVF,TnnT2,nkx2.5,MEF-2c,PECAM-1,IVSd,LVIDd,LVPWd,IVSd,LVIDs,LVPWd,EDV,ESV,FS
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