Towards a blood-based diagnostic panel for bipolar disorder

Frieder Haenisch,J D Cooper,Andreas Reif,Sarah Kittelschneider,Johann Steiner,F Markus Leweke,Matthias Rothermundt,Nico J M Van Beveren, Benedicto Crespofacorro,David W Niebuhr,David N Cowan,Natalya S Weber,Robert H Yolken,Brenda W J H Penninx,Sabine Bahn

Brain, Behavior, and Immunity（2016）

Cited 49|Views52

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Abstract

•A panel of 20 biomarkers was identified capable of differentiating BD patients from controls.•Excellent discrimination between established BD patients and controls.•Good to excellent discrimination between misdiagnosed BD patients and first onset MDD patients.•Fair to good discrimination between pre-diagnostic BD patients and controls.•Study demonstrates the potential utility of a protein biomarker panel as a diagnostic test for BD.

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Key words

Bipolar disorder,Multiplex immunoassay,Biomarker,Differential diagnosis,Diagnostic test

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