Design, synthesis and biological evaluation of biphenylurea derivatives as VEGFR-2 kinase inhibitors (II)
Chinese Chemical Letters（2016）
Abstract
In an effort to discover potent VEGFR-2 inhibitors, a series of O-linked biphenylurea derivatives were designed and synthesized. The structural activity relationships led to identification of a potential VEGFR-2 inhibitor compound 39.
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Key words
Angiogenesis,Kinase,Inhibitor,VEGFR-2
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