Effects of Lys-linked Dimerization of an α-Helical Leu/Lys-rich Model Antimicrobial Peptide on Salt Resistance and LPS-neutralizing Activity

Division of Magnetic Resonance, Korea Basic Science Institute, Chungbuk 363-883, KoreaReceived July 4, 2011, Accepted September 2, 2011Key Words : α-Helical model antimicrobial peptide, LPS-neutralizing activity, Lys-linked dimerization, SaltresistanceAntimicrobial peptides (AMPs) exhibit potent antimicro-bial activities against Gram-positive and Gram-negativebacteria, fungi and viruses and serve as part of their innateimmunity to pathogen invasion.