Synthesis of α,β-Unsaturated 2-Oxopyrrolidinyl Acetamide Derivatives by Application of the Ugi/RCM Reaction Sequence

E-mail: gkeum@kist.re.krReceived April 20, 2011, Accepted April 22, 2011Key Words : Ugi reaction, Multicomponent reaction, Piracetam, Nootropics, Lactam The Ugi four-component condensation reaction have beenwidely used for the construction of focused library anddiversity-oriented approach especially in the drug discovery,and also applied to introduce more complexity by utilizingbifunctional components or post transformations.