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Contact lens wear ocular discomfort and changes to inflammatory mediators in human tears

Simin Masoudi,Zhenjun Zhao,Amali Ariyavidana,Jennie Diec,Pauline Xu,Mark Willcox

Contact Lens and Anterior Eye（2012）

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Abstract
Purpose: End of day ocular discomfort has been reported both with contact lens wear (CLW) and with no lens wear (NCLW). Changes in the concentration of inflammatory mediators in the tear film may play a role in ocular dryness and discomfort. This study aimed at correlating diurnal changes of inflammatory mediators with subjective comfort ratings, in CLW and NCLW.
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Key words
ocular discomfort,lens,inflammatory mediators,wear
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