Immobilization of cross linked Col-I–OPN bone matrix protein on aminolysed PCL surfaces enhances initial biocompatibility of human adipogenic mesenchymal stem cells (hADMSC)

Younghee Kim,Md Anirban Jyoti,Hoyeon Song

Applied Surface Science（2014）

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摘要

•Poly-ɛ-caprolactone film surfaces have been modified through aminolysis and immobilization of COL-1 and OPN.•Surface characterization showed successful immobilization.•In vitro studies showed human adipogenic messenchymal stem cells (hADMSC) proliferate on modified surfaces which is beneficial for bone tissue engineering.

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关键词

Aminolysis,Poly-ɛ-caprolactone,Col-I–OPN,hADMSC,Biofunctionalization

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