Cardiomyocyte injury induced by hemodynamic cardiac stress: Differential release of cardiac biomarkers

•Hemodynamic cardiac stress, as quantified by BNP levels, is more closely reflected by concentrations of hs-cTnT, cTnI-ultra and Myoglobin than CK-MB.•The strong correlation between the amount of hemodynamic cardiac stress and the amount of cardiomyocyte injury seems to be restricted to patients in the highest tertile•Increased hemodynamic stress and myocardial injury is commonly seen among acute chest pain patients, even among those diagnosed with a non-cardiac cause of chest pain.