In-line optical monitoring of oxygen saturation and hematocrit for cardiopulmonary bypass: Adjustment-free and bloodless calibration

AbstractBackground and objective:This article describes a new sensor for monitoring oxygen saturation (sOMaterials and methods:The optical sensor presented here uses near-infrared spatially resolved reflectance spectroscopy. The primary calibration model for a master sensor is derived from the measurement of circulating human blood from a number of different patients with references taken from standard laboratory analysis of blood parameters. Transfer of the calibration model from the master sensor to new sensors is performed by measurement of an optical standard made of artificial material with defined and controlled optical properties.Results:The predicted values of sOConclusion:A new sensor with high degree of accuracy for sO