Long Term Effect of Immunotherapy for Japanese Ceder Pollinosis

From 1980 to 1986, 254 patients with nasal allergy were found to have sensitivity to Japanese Ceder Pollen at the ENT allergic clinic of Nippon Medical School. These patients were divided into two groups, one was treated with immunotherapy untill May 1987. Questionnaire were mailed to all the patients asking about severity of nasal symptom at the time of the first visit and after immunotherapy, and whether or not they were being treated with other methods for the last few seasons.Answers were received from 144 patients. Improvement after the immunotherapy was noted 27% for 6 months, 48% for 7-24 months, 50% for 25 months or more of the immunotherapy.Of 73 patients in the non-immunotherapy group 36% improved. There was no statistically significant difference in improvement between the immunotherapy group and the non-immunotherapy. Improvement at present time was noted 33% for 6 mouths, 37% for 7-24 months, 65% for 25 months or more of the immunotherapy with a significant difference compared with the non-immunotherapy group in which improvement noted 36%. In the percentage of the patients received other methods at present time there was no significant difference between the immunotherapy group and the non-immunotherapy.