Simultaneous Injection Effective Mixing Flow Analysis (SIEMA): Its Development and Application

The development and application of a new simultaneous injection- effective mixing flow analysis (SIEMA) is described. The manifold is based on one syringe pump with a two-way solenoid valve, a set of holding coils and three-way solenoid valves, two multiport connectors, a mixing coil and a detector. The system is compact and is controlled by a laptop computer. Some analytical features of SIEMA are compared with other flow-based systems in terms of mixing efficiency, reagent consumption and sample throughput. Applications of the SIEMA system are demonstrated for environmental and clinical analysis.