Central retinal vein occlusion with secondary cilioretinal artery occlusion treated with intravitreal bevacizumab (Avastin)

Two young male patients experienced acute visual disturbance in one eye, with central scotoma showing central retinal vein occlusion with cilioretinal artery occlusion (CLRAO). Optical coherent tomography (OCT) revealed inner retinal edema at areas of retinal infarction. An intravitreal injection of Avastin was administered to these two patients with improvement of symptoms within 4–8 weeks. These two cases suggested that OCT may help detect CLRAO by showing inner retinal edema, and demonstrated that intravitreal injection of Avastin may improve venous engorgement and retinal hemorrhage, as well as circulation of cilioretinal artery, thus shortening the disease course.