Monitoring model drug microencapsulation in PLGA scaffolds using X-ray powder diffraction
Saudi Pharmaceutical Journal(2016)
摘要
The microencapsulation of three model drugs; metronidazole, paracetamol and sulphapyridine into Poly (dl-Lactide-Co-Glycolide) (PLGA) scaffolds were probed using X-ray Powder Diffraction (XRPD). Changes in the diffraction patterns of the PLGA scaffolds after encapsulation was suggestive of a chemical interaction between the pure drugs and the scaffolds and not a physical intermixture.
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关键词
Encapsulation,PLGA,Model drugs,XRPD
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