Inhibitors of cyclic nucleotide phosphodiesterases produced by streptomyces. I. Reticulol, an inhibitor of cyclic nucleotide phosphodiesterases.
AGRICULTURAL AND BIOLOGICAL CHEMISTRY(1977)
Abstract
About 1, 200 microbial cultured filtrates have been screened for inhibition of cyclic nucleotide phosphodiesterases (EC 3. 1. 4. c] prepared from rabbit brains. One of the active agents was isolated and identified as reticulol (6, 8-dihydroxy-7-methoxy-3-metbylisocoumarin).
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Key words
cyclic nucleotide phosphodiesterases,streptomyces,inhibitors,inhibitors
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