IL-2, IL-15 and IL-21 expand T cells for targeted adoptive therapy

Zhenjiang Liu,Qingda Meng,Markus Maeurer,Elena Rangelova,Thomas Poiret, Rebecca Robertson,Aditya Ambati,Lalit Rane,Jiri Bartek,Caroline Verbeke,Oscar Persson,Matthias Löhr,Ralf Segersvärd,Ernest Dodoo

Journal for ImmunoTherapy of Cancer（2015）

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摘要

Meeting abstracts Expansion of antigen-specific T cells, from peripheral blood specific for tumor-associated antigens (TAAs) is a prerequisite for the advanced cellular therapy. Such antigen-specific T cells should express a Th1-functional phenotype and are able to enter tumor-tissue. We identified

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关键词

TAA, T cells, IL-2, IL-15, IL-21, adoptive T cell therapy

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