MLL-ELL fusion gene in an acute myelomonocytic leukemia patient transformed from acute promyelocytic leukemia.

Wang Qiang Hu,Xiao Xia Wang,Rong Rong Yang,Kang Yu

CLINICAL CASE REPORTS（2015）

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摘要

We report an extremely rare case of acute myelomonocytic leukemia (M4) with an MLL-ELL fusion gene lacking the PML-RARα rearrangement that transformed from hypergranular acute promyelocytic leukemia (APL) without showing any karyotypic evolution. The treatment was effective with chemotherapy for M4 and idarubicin plus a cytarabine-based chemotherapy protocol without ATRA.

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关键词

Acute myelomonocytic leukemia,MLL-ELL,Transform,acute promyelocytic leukemia

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