Application of Laser Spray for Liquid Chromatography/Mass Spectrometry Interface

New liquid chromatography/mass spectrometry (LC/MS) coupled with a new interface, LC/laser spray MS was developed. The laser spray was found to be particularly suitable for the low-concentration aqueous sample solutions because the enrichment of the sample concentration takes place near the meniscus of the liquid sample protruded from the stainless steel capillary. The extracts from the young leaves were measured using the present method coupled with the dual spray technique. Owing to much better sensitivities for laser spray than for electrospray, molecular formulas for some components in the sample could be postulated.