Efeito antibacteriano e anti-inflamatório tópico do extrato metanólico deChenopodium ambrosioides L.
Revista Fitos Eletronica(2015)
摘要
The use of medicinal plants is a common practice in countries as part of popular culture as a treatment of different
pathologies. The Chenopodium ambrosioides L. plant, popularly known as Mastruz, is used in folk medicine to
treat chronic bronchitis, tuberculosis, bruises, fractures and hernias, and some activities scientifically proven as
anthelmintic and antimicrobial action. Thus, this study aimed to evaluate the chemical profile and investigate the
antibacterial activity, modulator of antibiotics and topical anti-inflammatory of methanol extract obtained from
Chenopodium ambrosioides L. leaves. In the phytochemical extract prospecting, they were checked different
metabolites that have multiple biological activity, and the dosage of total phenols were checked 21.0 mg / g gallic
acid equivalent, and the quantification of flavonoids found a total of 135.4 mg / g quercetin. There was no
antibacterial activity, but modulation was detected when the extract was associated with aminoglycosides against
strains of E. coli and Staphylococcus aureus. In tests for acute inflammation, the extract showed an
antiedematogenic potential at concentrations of 25 and 50 mg. Given the results, we can correlate the empirical
knowledge of people; the biological properties observed in this study, this may be important for future validation
of these ethnomedicinal properties.
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关键词
minimum inhibitory concentration,modulation
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