TRP channel mediated neuronal activation and ablation in freely behaving zebrafish

Nature Methods(2015)

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摘要
Heterologous TRP channels can be used to stimulate or ablate neurons in response to their chemical or thermal agonists in zebrafish larvae, providing a set of tools orthogonal to optogenetic manipulation.
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关键词
Behavioural methods,Genetic models,Neuroscience,Patch clamp,Zebrafish,Life Sciences,general,Biological Techniques,Biological Microscopy,Biomedical Engineering/Biotechnology,Bioinformatics,Proteomics
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