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乙肝患者HBeAg含量与其临床、病理及HBV DNA的关系

柳龙根,方国平, 马春明,翟德芳,钱梅云

mag（2004）

Cited 23|Views3
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Abstract
检测326例未经抗病毒治疗的乙肝患者血清HBeAg和HBV DNA含量,49例进行了肝活检.结果:临床各型乙肝中除慢性轻度外,其余各组HBeAg阳性率比HBV DNA阳性率低(P＜0.01);慢性乙肝轻度、中度、重度、肝硬化、重型肝炎的HBeAg含量无显著性差异(P＞0.05);HBeAg与HBVDNA含量呈正相关(r=0.339,P=0.0001),病理炎症分级G1～G4和纤维化分期S1～S4各组间HBeAg含量均无明显差异(P＞0.05).提示乙肝患者血清HBeAg和HBV DNA含量呈正相关,但不能反映其病情的严重程度,与肝组织病理炎症分级和纤维化分期无明显相关性.
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