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雌激素合成及代谢基因的多态性与乳腺癌易感性

姜永冬,刘晶,庞达

Journal of International Oncology（2009）

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Abstract
雌激素是乳腺癌的主要危险因素,推测是通过雌激素受体影响乳腺癌的发病风险.因此,与雌激素合成和代谢相关的基因多态性被认为是乳腺癌的主要危险因子.与雌激素合成基因(CYP11A1、CYP17、CYP19)和代谢基因(CYP1A1、CYP1B1、CYP1A2)相关的基因多态性在调节乳腺癌易感性中具有一定意义.
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Key words
genes,biosynthesis,risk factors,breast cancer
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