Measuring protein flexibility with terahertz spectroscopy: basic research and applications

A G Markelz,J Y Chen,Joseph R Knab,Morgan L Maeder

Digest of the LEOS Summer Topical Meetings Biophotonics/Optical Interconnects and VLSI Photonics/WBM Microcavities, 2004.（2004）

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摘要

We have used terahertz time domain spectroscopy (TTDS) to measure protein dielectric response and investigate conformational vibrational modes. The bacteriorhodopsin discuss our more recent work on cytochrome c. Bacteriorhodopsin is a photoactive membrane protein from halobacterium salinarum.

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关键词

proteins,bacteriorhodopsin,membrane protein,microorganisms,vibrational modes,terahertz time domain spectroscopy,cytochrome c,spectroscopy,fluctuations,terahertz

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