Enhancing T cell persistence of CAR-redirected T cells in solid tumors
Journal for ImmunoTherapy of Cancer(2014)
Abstract
Meeting abstracts T cell persistence is likely to promote long-term anti-tumor effects after adoptive T cell transfer. We have recently shown that incorporation of the ICOS intracellular domain into chimeric antigen receptors (CARs) significantly increased Th17 cell persistence in vivo , compared
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Key words
Th17 Cell, Antitumor Effect, Antigen Receptor, Chimeric Antigen Receptor, Tumor Infiltration
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