In vitro investigation of the antiproliferative and proapoptotic effects of hyperatomarin – a bicyclic prenylated acylphloroglucinol from Hypericum annulatum Moris subsp. annulatum against human tumor and endothelial cells

Georgi Momekov,Sefedin Biljali,Paraskev T Nedialkov,Dimitrina Zhelevadimitrova,Gerassim M Kitanov,Denitsa Momekova,Nikolay Stoyanov,Margarita Guenova,Antoaneta Michova,Margarita Karaivanova

journal of Pharmaceutical Technology and Drug Research（2012）

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摘要

Background: Hyperatomarin is an acylphloroglucinol isolated from H. annulatum Moris subsp. annulatum, a species endemic for Sardinia and the Balkan Peninsula. Preliminary studies have shown antibacterial

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apoptosis,cytotoxicity

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