The common feature of cancer-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to the oncometabolite 2-hydroxyglutaratePatrick S Wardmag(2013)引用 23|浏览0暂无评分AI 理解论文溯源树样例生成溯源树,研究论文发展脉络Chat Paper正在生成论文摘要