Synthesis of Thiophene Acetylenes via Sonogashira Cross- Coupling Reactions

Organochalcogene compounds (S, Se and Te) have been investigated in recent decades because of their many applications in synthetic organic chemistry, preparation of new materials, and medicinal chemistry. Among them, the thiophene group has emerged in recent years as one of the most-studied compounds by synthetic organic chemists, due to being found in various chemical compounds, with a broad range of applications in the electronics industry to produce electroluminescent diodes (OLED), organic field effect transistors (OFET), photovoltaic cells, sensors, semiconductors, liquid crystals and displays. 1 Because of the strong interest in the synthesis of new thiophene compounds and its applications, in this communication we show our results in the synthesis of thiophene acetylenes through Sonogashira cross coupling reactions. 2